Human Cytomegalovirus Epitope Dominant Selection of a Public TCR against a Structural Bases for the Affinity-Driven
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منابع مشابه
Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope.
Protective T cell responses elicited along chronic human CMV (HCMV) infections are sometimes dominated by CD8 T cell clones bearing highly related or identical public TCR in unrelated individuals. To understand the principles that guide emergence of these public T cell responses, we have performed structural, biophysical, and functional analyses of an immunodominant public TCR (RA14) directed a...
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تاریخ انتشار 2009